HIV-1 protease-IN-10 (Compound 2) has HIV-1 latency reversing activity ( IC 50 : 0.22 μM). HIV-1 protease-IN-10 binds to the PKCδ C1b domain ( IC 50 : 0.69 μM). HIV-1 protease-IN-10 has stability against esterase-mediated hydrolysis.
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