BET BD2-IN-1 (compound 45) is a potent and selective inhibitor of BET BD2 ( IC 50 =1.6 nM). BET BD2-IN-1 inhibits the differentiation of Th17 cells by decreasing the activation of STAT3 and NF-κB . BET BD2-IN-1 is used in psoriasis and inflammatory bowel disease (IBD) research.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Epigenetic Reader Domain
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