Anti-inflammatory agent 56 (Compound 9) is a selective COX-2 inhibitor ( IC 50 : 0.54 μM). Anti-inflammatory agent 56 has anti-oxidant and anti-inflammatory effects. Anti-inflammatory agent 56 inhibits oxidative stress induced cell death. Anti-inflammatory agent 56 inhibits oxidative stress and neuroinflammation by inhibiting Keap1, COX-2 and iNOS . Anti-inflammatory agent 56 has low acute toxicity in mice (LD 50 : 1000 mg/kg).
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > COX
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