JT001 (NLRP3-IN-19) is a potent, specific and orally active inhibitor of NLRP3 . JT001 can inhibit NLRP3 inflammasome assembly, resulting in the inhibition of cytokine release and the prevention of pyroptosis . JT001 can be used for the research of nonalcoholic steatohepatitis and liver fibrosis.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > NOD-like Receptor (NLR)
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