NH2-methylpropanamide-Exatecan TFA

Overview

NH2-methylpropanamide-Exatecan TFA is a methylpropanamide-modified Exatecan ( HY-13631 ), which is the common ADC Cytotoxin used in the synthesis of ADC. Exatecan is a DNA topoisomerase I inhibitor, with an IC50 of 2.2 μM (0.975 μg/mL), and can be used in cancer research.

Application

Products | Products > Signaling Pathways > Antibody-Drug Conjugate/ADC Related | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > ADC Payloads | Products > Signaling Pathways > Topoisomerase

Product Information

• Catalog No.: HY-156686
• CAS No.: 1817857-35-4
• Molecular Formula: C30H30F4N4O7
• Molecular Weight: 634.58
• Purity: 99.80%
• Storage: -20°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 1.25 mg/mL (1.97 mM); Clear solution
• Availability: In-stock

Source

Original product source