BAY-1128688

Overview

BAY-1128688 is a potent, orally active and selective AKR1C3 inhibitor with IC 50 < 2 nM. BAY-1128688 shows high selectivity over related AKR1C enzymes (1C1, 1C2, 1C4) and AKR1D1. BAY-1128688 exhibits no relevant activity at major nuclear hormone receptors. BAY-1128688 reduces endometriotic lesions in the marmoset monkey endometriosis model. BAY-1128688 can be used for endometriosis research.

Application

Products | Products > Disease Areas > Urogenital Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Female Reproductive System Disease | Products > Disease Areas > Endometriosis | Products > Research Areas > Metabolic Disease | Products > Research Areas > Endocrinology

Product Information

• Catalog No.: HY-156701
• CAS No.: 1428988-21-9
• Molecular Formula: C28H31FN2O3
• Molecular Weight: 462.56
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source