GKA50

Overview

GKA50 is a potent glucokinase activator ( EC 50 =33 nM at 5 mM glucose). GKA50 stimulates insulin release from mouse islets of Langerhans. GKA50 is a glucose-like activator of beta-cell metabolism in rodent and human islets and a Ca 2+ -dependent modulator of insulin secretion. GKA50 shows significant glucose lowering in high fat fed female rats.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Glucokinase

Product Information

• Catalog No.: HY-15671
• CAS No.: 851884-87-2
• Molecular Formula: C26H28N2O6
• Molecular Weight: 464.51
• Purity: 99.84%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source