CCW 28-3 is a BRD4 PROTAC degrader. CCW 28-3 recruits RNF4 to BRD4 , inducing RNF4 -dependent ubiquitination and proteasomal degradation of BRD4 . CCW 28-3 can be used in breast cancer-related research. (Pink: BRD4 ligand ( HY-78695 ); Blue: RNF4 ligand ( HY-143346 ); Black: linker ( HY-170384 )).
Products | Products > Disease Areas > Cancer | Products > Disease Areas > Breast Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > Epigenetic Reader Domain
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