JAK-IN-34 (compound 11n) is a potent against of JAKs with IC 50 values of 0.40, 0.83, 2.10, 1.95 nM target JAK1 , JAK2 , JAK3 , TYK2 , respectively. JAK-IN-34 reduces joint swelling with good safety.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > JAK/STAT Signaling | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > JAK
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