EP3 antagonist 6 (compound 5) is a potent, orally and selective EP3 receptor antagonist, with an IC 50 of 1.9 nM. EP3 antagonist 6 can inhibits PGE2-induced ( HY-101952 ) uterine contraction in pregnant rats.
Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Endocrinology | Products > Signaling Pathways > Prostaglandin Receptor
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