PROTAC (H-PGDS)-8 is an H-PGDS PROTAC inhibitor with a IC 50 of 0.14 μM. PROTAC (H-PGDS)-8 binds to H-PGDS and inhibits its enzymatic activity. PROTAC (H-PGDS)-8 inhibits the production of PGD 2 in cancer cells. PROTAC (H-PGDS)-8 can be used for the research of Duchenne muscular dystrophy. (Pink: Target protein ligand; Blue: Cereblon ligand ( HY-W460193 ); Black: linker).
Products | Products > Disease Areas > Musculoskeletal and Skin Disease | Products > Disease Areas > Muscle Disease | Products > Disease Areas > Duchenne Muscular Dystrophy | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > Prostaglandin Receptor
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