MS39

Overview

MS39 (compound 6) is a PROTAC targeting EGFR . MS39 reduces the expression of EGFR and downstream signaling in HCC-827 and H3255 cells. MS39 inhibits the proliferation of H3255 cells. (Pink: EGFR ligand ( HY-W109039 ); Blue: VHL ligand ( HY-125845 ); Black: linker ( HY-W014125 )).

Application

Products | Products > Disease Areas > Respiratory Cancer | Products > Disease Areas > Non-Small Cell Lung Cancer | Products > Disease Areas > Cancer | Products > Disease Areas > Respiratory Disease | Products > Disease Areas > Lung Cancer | Products > Signaling Pathways > JAK/STAT Signaling | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > PROTAC | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > EGFR | Products > Signaling Pathways > PROTACs

Product Information

• Catalog No.: HY-157581
• CAS No.: 2675490-92-1
• Molecular Formula: C55H71ClFN9O7S
• Molecular Weight: 1056.72
• Purity: 99.89%
• Storage: -20°C, protect from light, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
• Availability: In-stock

Source

Original product source