NLRP3-IN-34 (Compound T10) is an inhibitor for NLRP3 inflammasome. NLRP3-IN-34 inhibits ROS production, NLRP3 inflammasome-dependent IL-1β production ( IC 50 is 0.48 μM in cells J774A.1), and inhibits pyroptosis . NLRP3-IN-34 exhibits anti-inflammatory activity against DSS-induced peritonitis.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > NOD-like Receptor (NLR)
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