BIO-8169

Overview

BIO-8169 is a selective inhibitor for interleukin receptor-associated kinase 4 ( IRAK 4 ), with an IC 50 of 0.23 nM. BIO-8169 exhibits good pharmacokinetic character, reduces the production of pro-inflammatory cytokines, and attenuates the autoimmune encephalomyelitis in EAE mice model. BIO-8169 exhibits good blood brain penetrant with a rat Kpu,u of 0.7.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > IRAK

Product Information

• Catalog No.: HY-158374
• CAS No.: 2792153-06-9
• Molecular Formula: C24H27N5O4
• Molecular Weight: 449.50
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source