AAK1-IN-6 (Compound 23) is an inhibitor of AP-2-associated protein kinase 1 ( AAK1 , IC 50 = 12 nM) with antiviral activity against the dengue virus (DNEV2, EC 50 = 0.24 μM) and Venezuelan equine encephalitis virus (VEEV, EC 50 = 0.30 μM). AAK1-IN-6 can be utilized in antiviral research.
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