Firefly luciferase-IN-2 (compound 5j) is an inhibitor of ATP-dependent luciferase ( Firefly luciferase ), the major light-emitting enzyme in fireflies and kowtow bugs. Firefly luciferase-IN-2 inhibits P. pyralis luciferase with an IC 50 of 0.15 μM, while the inhibitory potency against R. reniformis is not significant.
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