HDL-16 is a potent P2Y 14 R antagonist with an IC 50 of 0.3095 nM. HDL-16 ameliorates DSS ( HY-116282C )-induced colitis through suppressing necroptosis of intestinal epithelium cells (IECs) and protecting mucosal barrier function.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Digestive System Inflammation | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > P2Y Receptor | Products > Signaling Pathways > Necroptosis
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