PDE4-IN-15 (compound 7b-1) is an inhibitor of PDE4 ( IC 50 = 0.17 μM) and has anti-TNF-α activity ( EC 50 = 0.19 μM). PDE4-IN-15 has a good skin permeability.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Phosphodiesterase (PDE) | Products > Signaling Pathways > TNF Receptor
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