XOR/URAT1-IN-1 (Compound II15) is a dual inhibitor for xanthine oxidoreductase ( XOR ) and uric acid transporter 1 ( URAT1 ), with IC 50 of 6 nM and 12.9 μM. XOR/URAT1-IN-1 lowers the levels of uric acid in Potassium oxonate ( HY-17511 )/Hypoxanthine ( HY-N0091 )-induced acute hyperuricemia mouse model.
Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Xanthine Oxidase | Products > Signaling Pathways > URAT1
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