Anemoside A3-methyl 6-aminohexanoate is an orally effective pyruvate carboxylase ( PC ) inhibitor with a K d value of 10.1 μM against human PC . Anemoside A3-methyl 6-aminohexanoate exerts its function through the PC/NF-κB/NLRP3 inflammasome axis. Anemoside A3-methyl 6-aminohexanoate significantly alleviates symptoms of DSS ( HY-116282C )-induced colitis in mice. Anemoside A3-methyl 6-aminohexanoate can be used in colitis-related research.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > NF-κB | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Pyruvate Carboxylase (PC) | Products > Signaling Pathways > NOD-like Receptor (NLR) | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Interleukin Related
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