PIK-293

PIK-293
  • CAS No.:900185-01-5
Other grades of this product :
PIK-293 Basic information
Product Name:PIK-293
Synonyms:PIK-293;2-[(4-Amino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)methyl]-5-methyl-3-(2-methylphenyl)-4(3H)-quinazolinone;2-((4-amino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)methyl)-5-methyl-3-o-tolylquinazolin-4(3H)-one;CS-539;2-[(4-aminopyrazolo[3,4-d]pyrimidin-1-yl)methyl]-5-methyl-3-(2-methylphenyl)quinazolin-4-one;PIK-293;PIK293;PIK 293;4(3H)-Quinazolinone, 2-[(4-amino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)methyl]-5-methyl-3-(2-methylphenyl)-;PIK-293 USP/EP/BP
CAS:900185-01-5
MF:C22H19N7O
MW:397.43
EINECS:
Product Categories:Akt;mTOR;Inhibitors;PI3K
Mol File:900185-01-5.mol
PIK-293 Chemical Properties
density 1.43
Safety Information
MSDS Information
PIK-293 Usage And Synthesis
DescriptionPIK-293 is a cell-permeable, selective inhibitor of the phosphatidylinositol 3-kinase (PI3K) catalytic subunit p110δ (IC50s = 100, 25, 10, and 0.24 μM for p110 subunit isoforms α, β, γ, and δ, respectively).
UsesPIK-293 is a phosphoinositide 3-kinase delta (PI3Kδ) inhibitor and the parent compound of PIK-294 (P437705). Inhibition of PI3K’s shows to be a promising approach for cancer therapy.
PIK-293 Preparation Products And Raw materials

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