BC-1293 is an inhibitor for E3 ligase subunit FBXO24 . BC-1293 disrupts the interaction between FBXO24 and aspartyl-tRNA synthetase (DARS2) and increases the level of DARS2. BC-1293 increases levels of IL-1β, IL-9 , MIP-2, and TNF α, and exhibits immunostimulatory activity in mice.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > E1/E2/E3 Enzyme
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