STAT6-IN-12 is a potent STAT6 inhibitor with an IC 50 of 50 nM. STAT6-IN-12 also inhibits Smad2/3 with an IC 50 of 68 nM. STAT6-IN-12 inhibits TGFβ -dependent Smad2/3 signaling pathway, IL-4 -dependent STAT6 signaling pathway, and cellular inflammatory responses. STAT6-IN-12 can be used for the research of inflammation.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > JAK/STAT Signaling | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > TGF-beta/Smad | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > STAT | Products > Signaling Pathways > TGF-beta/Smad | Products > Signaling Pathways > Interleukin Related
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