SJ45566

Overview

SJ45566 a potent and orally active PROTAC-based LCK degrader, with a DC 50 of 1.21 nM. SJ45566 can be used in the research for T‑Cell Acute Lymphoblastic Leukemia. (Pink: Lck ligand ( HY-175916 ); Blue: Cereblon ligand ( HY-150839 ); Black: linker ( HY-W262798 )).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > Src

Product Information

• Catalog No.: HY-162676
• CAS No.: 3081937-95-0
• Molecular Formula: C37H42ClN9O3S
• Molecular Weight: 728.31
• Purity: 98.41%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 5 mg/mL (6.87 mM); Clear solution
• Availability: In-stock

Source

Original product source