FABP4-IN-3 (compound C3) is a highly selective FABP4 inhibitor (FABP4 K i = 25 ± 3 a nM, FABP3 K i = 15.03 μM) which exhibits a 601-fold selectivity over FABP3. FABP4-IN-3 also shows metabolic stability and potent cellular anti-inflammatory activity, making it promising to get involved in the research of metabolic disease , cardiac dysfunction and inflammation-related disease.
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