Antituberculosis agent-10 (Compound 9) has excellent antibacterial activity against Mycobacterium tuberculosis ( MIC = 0.3 μM ). Antituberculosis agent-10 inhibits protein synthesis by targeting the 50S ribosomal subunit of the bacterium, thus exerting its antibacterial effect. Antituberculosis agent-10 is orally active.
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