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| S- (+)-Rolipram Basic information |
| Product Name: | S- (+)-Rolipram | | Synonyms: | (S)-(+)-ROLIPRAM;(4S)-4-(3-(Cyclopentyloxy)-4-methoxyphenyl)pyrrolidine-2-one;Rolipram (S)-(+)-;(4S)-(3-(Cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one;(4S)-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]PYRROLIDIN-2-ONE;(+)-ROLIPRAM;(S)-ROLIPRAM;(4S)-4-[3-(cyclopentoxy)-4-methoxy-phenyl]-2-pyrrolidone;(S)-4-[3-(Cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone | | CAS: | 85416-73-5 | | MF: | C16H21NO3 | | MW: | 275.34 | | EINECS: | | Product Categories: | Signalling;Cyclic Nucleotide related;Inhibitors | | Mol File: | 85416-73-5.mol |
| S- (+)-Rolipram Chemical Properties |
| Melting point | 133-136℃ | | density | 1.155 | | storage temp. | Sealed in dry,Store in freezer, under -20°C | | form | White to off-white solid. | | color | White to Almost white |
| S- (+)-Rolipram Usage And Synthesis |
| Uses | S-(+)-Rolipram inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM, has anti-inflammatory and anti-depressant activity in the central nervous system, less potent than its R enantiomer | | Uses | S-(+)-Rolipram is an inhibitor of cyclic AMP-specific phosphodiesterase. It is the S isomer of (±)-Rolipram (R640040). Potent PDE4 inhibitor | | Definition | ChEBI: The (S)-enantiomer of rolipram. | | Biological Activity | Less active enantiomer of the PDE4 inhibitor rolipram (4-(3-(Cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one ). |
| S- (+)-Rolipram Preparation Products And Raw materials |
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