6-THIOGUANOSINE

6-THIOGUANOSINE
  • CAS No.:85-31-4
Other grades of this product :
6-THIOGUANOSINE Basic information
Product Name:6-THIOGUANOSINE
Synonyms:Guanosine, 6-thio-;ANTI-TXNRD3 (CENTER) antibody produced in rabbit;Thioredoxin and glutathione reductase;Thioredoxin reductase 3;TRXR3;TXNRD3;2-Amino-6-mercaptopurine-9-D-riboside;2-AMINO-6-MERCAPTOPURINE RIBOSIDE
CAS:85-31-4
MF:C10H13N5O4S
MW:299.31
EINECS:201-597-2
Product Categories:Nucleotides and Nucleosides;Bases & Related Reagents;Nucleotides;Sulfur & Selenium Compounds
Mol File:85-31-4.mol
6-THIOGUANOSINE Chemical Properties
Melting point 230-231°C
Boiling point 756.9±70.0 °C(Predicted)
density 2.18
refractive index 1.6460 (estimate)
storage temp. Keep in dark place,Sealed in dry,Store in freezer, under -20°C
pka13.21±0.70(Predicted)
CAS DataBase Reference85-31-4(CAS DataBase Reference)
Safety Information
Safety Statements 24/25
RTECS UP0200000
HS Code 29349990
ToxicityLD50 intraperitoneal in mouse: 156mg/kg
MSDS Information
6-THIOGUANOSINE Usage And Synthesis
Chemical PropertiesTan Powder
Usesantineoplastic
Purification MethodsThioguanosine is crystallised (as hemihydrate) from hot H2O (charcoal) and cooled slowly to give tapered prisms. It also crystallises by dissolving in dilute NH3 and acidifying with acetic acid, and then recrystallising from H2O. UV: (pH 4-6) max at 257nm ( 8,820) and 342nm ( 24,800), and (pH 10.4-12.0) max at 252nm ( 14,700) and 319.5nm ( 21,000). [Fox et al. J Am Chem Soc 80 1667 1958, Beilstein 26 III/IV 3927.]

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