PROTAC SMARCA2 degrader-12

Overview

SMARCA2 degrader-13 (compound I-406) is a PROTAC degrader targeting SMARCA2 ; it degrades SMARCA2 proteins in A549 cells with an DC 50 <100 nM, and a maximum degradation rate (Dmax%) >90 after 24 h of treatment. (Pink: SMARCA2 ligand ( HY-159545 ); Blue: VHL ligand ( HY-163951 ); Black: linker ( HY-W006635 )).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > PROTACs

Product Information

• Catalog No.: HY-163874
• CAS No.: 2568277-42-7
• Molecular Formula: C49H57N11O5S
• Molecular Weight: 912.11
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source