TLR4-IN-1 (compound 3k) inhibits the cell viability of RAW264.7 with an IC 50 of 1.02 μM. TLR4-IN-1 inhibits the release of cytokine TNF-α, IL-1β and IL-6 , and exhibits anti-inflammatory efficacy in rats rheumatoid arthritis models.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Toll-like Receptor (TLR)
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