INI-4001

Overview

INI-4001 is a TLR7/8 agonist and vaccine adjuvant . INI-4001 regulates innate and adaptive immune responses by activating murine TLR7 and human TLR7/TLR8 . INI-4001 enhances IgG and neutralizing antibody responses against Powassan virus (POWV) , reduces viral loads in the brain, liver and spleen, provides complete protection against lethal POWV challenge, and skews immune responses toward a Th1 phenotype. When INI-4001 is used in combination with Al (OH) 3 and SARS-CoV-2 RBD antigen, it efficiently adsorbs to Al (OH) 3 , promotes Th1 immunity and enhances SARS-CoV-2 neutralizing antibody responses. INI-4001 is applicable to research related to Powassan virus infection and COVID-19.

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Coronavirus Infection | Products > Disease Areas > SARS-CoV-2 Infection | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > Toll-like Receptor (TLR) | Products > Signaling Pathways > SARS-CoV

Product Information

• Catalog No.: HY-164485
• CAS No.: 2549050-07-7
• Molecular Formula: C59H109N6O13P
• Molecular Weight: 1141.50
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source