Neltenexine

Overview

Neltenexine, a mucolytic agent, is an Elastase inhibitor. Neltenexine diminishes anion secretion in in bronchial epithelial cells by inhibiting the Cl− and HCO3- uptake via Na/K/2Cl++− and Na+/HCO3- cotransporter without blockade of the CFTR channel, and also diminishes anion secretion via stimulation of Cl−/HCO3- exchanger. Neltenexine significantly prevents pulmonary emphysema with a reduction of alveolar deformation in rat models induced by Elastase . Neltenexine can be used for lung diseases such as chronic obstructive pulmonary disease (COPD) research.

Application

Products | Products > Disease Areas > Respiratory Disease | Products > Disease Areas > Pulmonary Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Elastase | Products > Signaling Pathways > CFTR

Product Information

• Catalog No.: HY-165407
• CAS No.: 99453-84-6
• Molecular Formula: C18H20Br2N2O2S
• Molecular Weight: 488.24
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source