BTS (N-Benzyl-p-toluenesulfonamide) is a potent and selective inhibitor of skeletal muscle myosin II subfragment 1 (S1) ATPase activity, with an IC 50 s of ~5 µM for actin- and Ca 2+ -stimulated myosin S1 ATPase. BTS specifically inhibits the contraction of fast skeletal muscle fibers.
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