PROTAC BRM/BRG1 degrader-2

Overview

PROTAC BRM/BRG1 degrader-2 (Example.004) is a PROTAC BRM/BRG1 degrader (DC 50 : < 10 nM in A549 cell; IC 50 : 15 nM for A549). (Pink: SMARCA2/BRM/BAF190B/SNF2L2 and SMARCA4/BRG1/BAF190A ligand ( HY-168248 ); Blue: VHL ligand ( HY-112078 ); Black: linker ( HY-168249 )).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > SWI/SNF Complex

Product Information

• Catalog No.: HY-168247
• CAS No.: 2933124-32-2
• Molecular Formula: C50H60N12O5S
• Molecular Weight: 941.15
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source