RNase L ligand 2 (compound 6) is the Rnase L ligand part of RNAse L RIBOTAC ( HY-168455 ), an RNA-degrading chimera which binds to a four-way RNA helix called SL5 in the 5’ UTR of the SARS-CoV-2 RNA genome and inhibits the virus replication in lung epithelial carcinoma cells. RNase L ligand 2 can be used in the synthesis of RIBOTAC.
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