IMPDH-IN-1 (compound 44) is a bacterial inosine 5'-monophosphate dehydrogenase ( IMPDH ) inhibitor. IMPDH-IN-1 specifically binds to the catalytic domain of IMPDH . IMPDH-IN-1 potently inhibits the IMPDH of Pseudomonas aeruginosa , Staphylococcus aureus and Escherichia coli .
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