FXR agonist 9 (compound 26) is an oral active and selectivity FXR partial agonist with the EC 50 of 0.09 µM (75.13 % maximum efficacy). FXR agonist 9 ameliorates pathological features in HFD and CCl 4 (HY-Y0298)-induced metabolic dysfunction-associated steatohepatitis mice.
Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > FXR
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