Protopanaxadiol

Protopanaxadiol
  • CAS No.:7755-01-3
Other grades of this product :
Protopanaxadiol Basic information
Product Name:Protopanaxadiol
Synonyms:Protopanaxadiol, 98%, from Panax ginseng C. A. Mey.;Protopanaxadiol;20R-Betulafolienetriol;(20R)-5α-Dammar-24-ene-3β,12β,20-triol;(20R)-Dammar-24-ene-3β,12β,20-triol;(20R)-Protopanaxadiol;20R-Protopanaxadiol;PROTOVERATRINE A+B (RG)(CALL)
CAS:7755-01-3
MF:C30H52O3
MW:460.73
EINECS:
Product Categories:Ginseng series;Miscellaneous Natural Products
Mol File:7755-01-3.mol
Protopanaxadiol Chemical Properties
Boiling point 559.5±40.0 °C(Predicted)
density 1.036±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,2-8°C
pka14.96±0.70(Predicted)
Safety Information
MSDS Information
Protopanaxadiol Usage And Synthesis
Description(20)R-Protopanaxadiol is a sapogenin that has been found in P. ginseng and has anticancer and antibacterial activities. It has a cytotoxic concentration (CC50) value of 6.1 μM in MT-4 human T cell leukemia cells and inhibits the growth of several additional cancer cell lines, including A549 human lung carcinoma, SKOV3 human ovarian adenocarcinoma, SK-Mel-2 human melanoma, P388 and L1210 murine leukemia, and K562 human chronic leukemia cells (ED50s = 11-26 μM). (20)R-protopanaxadiol also inhibits the growth of H. pylori in vitro (MICs = 50-100 μg/ml).
Uses20(R)-Protopanaxdiol is a saponin ginsenoside which is a signature phytochemical of Ginseng, an herbaceous plant. Anti-cancer agent.
DefinitionChEBI: A diastereomer of protopanaxadiol in which the 20-hydroxy substituent has been introduced at the pro-R position.
Protopanaxadiol Preparation Products And Raw materials
Raw materials20(R)-Ginsenoside Rg3

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