(-)-TEPHROSIN

CAS No.：76-80-2

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This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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(-)-TEPHROSIN Basic information

Product Name:	(-)-TEPHROSIN
Synonyms:	13,13a-Dihydro-7a-hydroxy-9,10-dimethoxy-3,3-dimethyl-3H-bis[1]benzopyrano[3,4-b:6',5'-e]pyran-7(7aH)-one;Hydroxydeguelin;Isotephrosin;Deguelinol I;Tephrosin (synthetic);3H-Bis[1]benzopyrano[3,4-b:6',5'-e]pyran-7- (7aH)-one,13,13a-dihydro-7a-hydroxy-9,10- dimethoxy-3,3-dimethyl-,(7aR,13aR)-;Tephrosin >=95% (LC/MS-ELSD);(-)-TEPHROSIN USP/EP/BP
CAS:	76-80-2
MF:	C23H22O7
MW:	410.42
EINECS:
Product Categories:	Miscellaneous Natural Products
Mol File:	76-80-2.mol

(-)-TEPHROSIN Chemical Properties

Melting point	198° (218-220°)
Boiling point	450.42°C (rough estimate)
density	1.2284 (rough estimate)
refractive index	1.5300 (estimate)
storage temp.	-20°C
pka	10.47±0.40(Predicted)

Safety Information

Hazard Codes	N
Risk Statements	50
Safety Statements	61
RIDADR	UN 3077 9 / PGIII
WGK Germany	3

MSDS Information

(-)-TEPHROSIN Usage And Synthesis

Uses	Tephrosin as a natural rotenoid obtained from Tephrosia vogelii and displays anticancer activity.
Definition	ChEBI: A member of the class of rotenones that is 13,13a-dihydro-3H-chromeno[3,4-b]pyrano[2,3-h]chromen-7(7aH)-one substituted with geminal methyl groups at position 3, hydroxy group at position 7a a d methoxy groups at positions 9 and 10 (the 7aR,13aR stereoisomer). It is isolated from the leaves and twigs of Antheroporum pierrei and exhibits antineoplastic and pesticidal activities.

(-)-TEPHROSIN Preparation Products And Raw materials

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