L-Alanosine (NSC-153353), an antibiotic from Streptomyces alanosinicus , has antineoplastic activity. L-Alanosine (NSC-153353) inhibits adenylosuccinate synthetase , which converts inosine monophospate (IMP) into adenylosuccinate. L-Alanosine is the inhibitor for methylthioadenosine phosphorylase ( MTAP ).
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