DBMB is an inhibitor of spleen tyrosine kinase ( Syk ), capable of significantly inhibiting the activity of Syk kinase. DBMB exhibits anti-inflammatory activity by suppressing the signaling of NF-κB , which in turn reduces the production of inflammatory mediators such as nitric oxide ( NO ) and prostaglandin E2 ( PGE2 ). DBMB can be utilized in research on inflammatory diseases.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Syk | Products > Signaling Pathways > NO Synthase | Products > Signaling Pathways > Prostaglandin Receptor
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