ZG297

Overview

ZG297 is an agonist for Staphylococcus aureus ClpP ( SaClpP ) with an EC 50 of 0.26 μM. ZG297 degrades SaFtsZ, inhibits the bacterial cell division, thereby exhibiting antistaphylococcal activity, that inhibits S. aureus 8325-4 strains and MRSA strains with MIC of 0.063-256 μg/mL. ZG297 exhibits anti-infectious efficacy in mouse models.

Application

Products | Products > Disease Areas > Infection | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > Antibiotic | Products > Signaling Pathways > Bacterial

Product Information

• Catalog No.: HY-170398
• CAS No.: 2999673-52-6
• Molecular Formula: C31H35F3N4O3
• Molecular Weight: 568.63
• Purity: 99.69%
• Storage: 4°C, protect from light, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
• Solubility: ≥ 2.5 mg/mL (4.40 mM); Clear solution
• Availability: In-stock

Source

Original product source