Cetagliptin is an orally active inhibitor for dipeptidyl peptidase 4 ( DPP-4 ) and CYP2D6 ( IC 50 of 6 µM). Cetagliptin is a substrate for P-glycoprotein . Cetagliptin reduces the GLP-1 degradation, maintains the level of postprandial blood sugar, and can be used in type 2 diabetes mellitus research.
Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Dipeptidyl Peptidase | Products > Signaling Pathways > Cytochrome P450 | Products > Signaling Pathways > P-glycoprotein
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