CDD-1431 is a low-nanomolar selective kinase inhibitors of BMPR2 , with K iapp value of 20.6 nM. CDD-1431 suppresses BRE-reporter activity, with an IC 50 of 4.87 μM. BMP controls cellular processes across many tissue types, including the kidney, skeletal muscle, heart, and reproductive organs. BMP induces ectopic bone formation.
Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > TGF-beta/Smad | Products > Research Areas > Endocrinology | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > TGF-β Receptor
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