Other grades of this product :
| PHA-793887 Basic information |
| Product Name: | PHA-793887 | | Synonyms: | N-(6,6-dimethyl-5-(1-methylpiperidine-4-carbonyl)-2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-yl)-3-methylbutanamide;CS-350;3-Methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]butanamide;PHA-793887;N-(6,6-dimethyl-5-(1-methylpiperidine-4-carbonyl)-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-yl)-3-methylbutanamide;3-Methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]butanamide PHA-793887;PHA-793887
3-Methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]butanamide;PHA-793887;PHA793887 | | CAS: | 718630-59-2 | | MF: | C19H31N5O2 | | MW: | 361.48 | | EINECS: | | Product Categories: | Inhibitors;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Protein Kinase Inhibitors and Activators;Apis | | Mol File: | 718630-59-2.mol |
| PHA-793887 Chemical Properties |
| Melting point | >147°C (dec.) | | Boiling point | 596.2±50.0 °C(Predicted) | | density | 1.176±0.06 g/cm3(Predicted) | | storage temp. | Hygroscopic, Refrigerator, under inert atmosphere | | solubility | DMSO (Slightly), Methanol(Slightly) | | pka | 13.74±0.40(Predicted) | | form | Solid | | color | Off-White to Pale Yellow | | Stability: | Hygroscopic |
| PHA-793887 Usage And Synthesis |
| Chemical Properties | White to Off-White Solid | | Uses | PHA-793887 is a potent CDK (cyclin-dependent kinase) inhibitor. Recent studies shows that PHA-793887 has promising therapeutic activity against acute leukemias in vitro and in vivo. PHA-793887 was used to successfully modulate E2F transcriptional factor-dependent cell cycle, DNA replication, mitosis and apoptosis related gene in both tumors and skin biopsy from patients with solid tumors. | | Uses | PHA-793887 is a potent CDK (cyclin-dependent kinase) inhibitor. Recent studies shows that PHA-793887 has promising therapeutic activity against acute leukemias in vitro and in vivo. PHA-793887 was used to successfully modulate E2F transcriptional factor-dependent cell cycle, DNA replication, mitosis and apoptosis related gene in both tumors and skin biopsy from patients with solid tumors. |
| PHA-793887 Preparation Products And Raw materials |
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