BCX-3607 is an orally active tissue factor/factor VIIa ( TF-FVIIa ) inhibitor ( IC 50 : 4 nM). BCX-3607 blocks the extrinsic coagulation pathway by inhibiting the TF-FVIIa complex and significantly prolongs the prothrombin time (PT). BCX-3607 has a higher selectivity for TF-FVIIa than other serine proteases (such as thrombin , FXa, etc.). BCX-3607 can reduce thrombus weight and inflammatory response, and has both anti-thrombotic and anti-inflammatory effects. BCX-3607 can be used in the study of thrombosis-related diseases.
Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Research Areas > Cardiovascular Disease
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