DEG-35

Overview

DEG-35 is a CRBN-dependent, dual IKZF2 and CK1α molecule glue degrader, with DC 50 values of 1.4 nM and 4.4 nM for CK1α and IKZF2 , respectively. DEG-35 activates the p53 apoptosis pathway. DEG-35 can be used in the research for Acute Myeloid Leukemia (AML).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Molecular Glues | Products > Signaling Pathways > Casein Kinase | Products > Signaling Pathways > IKZF Family

Product Information

• Catalog No.: HY-172931
• CAS No.: 2734910-37-1
• Molecular Formula: C25H21N3O5
• Molecular Weight: 443.45
• Purity: 98.88%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source