ASK1-IN-8 (Compound 35) is an orally active inhibitor of apoptosis signal-regulating kinase 1 ( ASK1 ) with an IC 50 value of 1.8 nM. In an experimental mouse model of liver injury induced by Acetaminophen ( HY-66005 ), ASK1-IN-8 can significantly reduce the plasma alanine transaminase ( ALT ) level, protecting the liver. ASK1-IN-8 can be used in research related to liver diseases.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > ASK1
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