AAK1-IN-8 (Compound 18) is a pan- NAK inhibitor. AAK1-IN-8 inhibits AAK1 and GAK ( EC 50 values are 50 and 190 nM, respectively). AAK1-IN-8 inhibits the phosphorylation of AP2-µ2 subunit at T156.
Products | Products > Disease Areas > Infection | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Infection | Products > Signaling Pathways > AAK1 | Products > Signaling Pathways > Cyclin G-associated Kinase (GAK)
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