Iptriazopyrid is a 4-hydroxyphenylpyruvate dioxygenase ( HPPD ) inhibitor, with a K i value of 24.3 nM against Arabidopsis thaliana and 33.3 nM against Oryza sativa . Iptriazopyrid binds to the active pocket of HPPD , occupies the catalytic site, inhibits carotenoid biosynthesis, prevents chloroplast formation, and induces albino and chlorotic symptoms in sensitive plants . Used as a herbicide , Iptriazopyrid can control barnyardgrass when applied alone, and its efficacy does not decrease when mixed with labeled residual herbicides. When Iptriazopyrid is mixed with 2,4-D or triclopyr, its barnyardgrass control effect shows an antagonistic effect. Iptriazopyrid is a triazole carboxamide herbicide that exhibits selectivity for Oryza sativa over Echinochloa crus-galli , and has partial tank-mix compatibility with synthetic auxin herbicides registered for rice.
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